| abstract |
A gene recombination system for producing a selenocysteine-containing protein at an expression level that can be used practically is constructed. Kind Code: A1 A gene sequence encoding an expression control region operable in an animal individual, a gene sequence encoding a target selenocysteine-containing protein, and a gene having a gene sequence encoding a selenocysteine insertion sequence (SECIS sequence) The expression unit is introduced into an animal cell, and then the animal cell is introduced into a mammal or a bird to produce a transgenic animal capable of expressing a target selenocysteine-containing protein. [Selection diagram] None |