| abstract |
The following general formula (1) Embedded image (Wherein, -A- is -CH 2 -CH 2 - group, -CH = CH- group, -CH (OH) -CH 2 - group or a -C (O) -CH 2 - represents a group, X is A benzoic acid derivative represented by an oxygen atom, an NH group or an S (O) n group (where n is an integer of 0, 1 or 2) or a salt thereof, and a medicament comprising the same as an active ingredient. [Effect] The compound of the present invention has an action of selectively activating α-type of PPAR, and is not accompanied by weight gain or obesity, hyperlipidemia, arteriosclerosis, diabetes, diabetic complications, inflammation, It is useful as a prophylactic and / or therapeutic agent for heart diseases and the like. [Selection diagram] None |