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filingDate 2003-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76572bc2100ee5c047e61235865eb2ef
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publicationDate 2004-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2004315434-A
titleOfInvention Method for producing trifluoromethyl-substituted 2-bromoacetophenone and trifluoromethyl-substituted 2-hydroxyacetophenone
abstract The present invention provides an industrial method for producing trifluoromethyl-substituted 2-bromoacetophenone and trifluoromethyl-substituted 2-hydroxyacetophenone, which are important intermediates of medicines and agricultural chemicals. A presence of alkylene diols trifluoromethyl substituted acetophenones, by bromination with Br 2, into a cyclic acetal of trifluoromethyl-substituted 2-bromoacetophenone, then acidic conditions, the water-reactive This produces trifluoromethyl-substituted 2-bromoacetophenone. Also, trifluoromethyl-substituted 2-hydroxyacetophenone is produced by reacting trifluoromethyl-substituted 2-bromoacetophenone with water under acidic or neutral conditions. By this method, trifluoromethyl-substituted 2-bromoacetophenone and trifluoromethyl-substituted 2-hydroxyacetophenone can be obtained much more efficiently than before. [Selection diagram] None
priorityDate 2003-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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