abstract |
PROBLEM TO BE SOLVED: To provide an agent for preventing or treating kidney disease. A compound that regulates (preferably inhibits) the activity of a protein having the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 1 or the expression of the protein gene, the protein or Antisense polynucleotides containing a nucleotide sequence complementary or substantially complementary to the nucleotide sequence of the DNA encoding the partial peptide or a part thereof, antibodies to the protein or its partial peptide, and the like, include diabetic nephropathy and the like. It is useful as a prophylactic / therapeutic agent for renal diseases and the like. [Selection diagram] None |