| abstract |
PROBLEM TO BE SOLVED: To provide a PDE4 inhibitor comprising a 6-phenyl-1,3,4,6,11,11a-hexahydro-2H-pyrazino [1,2-b] isoquinoline compound or a pharmaceutically acceptable salt thereof as an active ingredient. I will provide a. SOLUTION: General formula [I]: Embedded image (In the formula, R 1 and R 2 are the same or different and each represents a hydroxyl group or a lower alkoxy group.) Or a pharmacologically acceptable salt thereof as an active ingredient. [Selection diagram] None |