| abstract |
The present invention provides a medicament useful for preventing and / or treating diseases involving cell death, such as cerebral infarction, Alzheimer's disease, Parkinson's disease, and Huntington's chorea, by inhibiting cell death-related protein kinase. . The following general formula (I): Embedded image (Wherein, R 1 to R 6 are each independently a hydrogen atom, a halogen atom, a nitro group, a lower alkyl group optionally having a substituent, a lower alkoxy group optionally having a substituent, A hydroxy group or an amino group which may have a substituent, R 7 represents a hydrogen atom or a lower alkyl group which may have a substituent, X and Y simultaneously represent a carbonyl group, One of which is a carbonyl group and the other one is a methylene group), and a substance selected from the group consisting of pyrrocarbazole derivatives and salts thereof, and solvates and hydrates thereof. A medicament for preventing and / or treating a disease caused by an abnormal increase in cell death-related protein kinase, including: |