| abstract |
A series of 3-alkyl-4-aminobutyric acid or 3-alkylglutamic acid analogs that are useful as anticonvulsants. A 3-alkyl-4-aminobutyric acid or 3-alkylglutamic acid analog which is an S (+) enantiomer represented by the formula (I). (X is -OH, -NH 2, -N 3 or p- toluenesulphonyloxy, Y is -CH 2 - or represents, or X-Y- is -COOH together .R is, X is -OH a -N 3 or p- toluenesulfonyloxy, Y is -CH 2 - or if it is, or X-Y- is -COOH together represent a benzyl or 1,1 dimethylethyl, Alternatively, R is, X is -NH 2, and, Y is -CH 2 -, it is hydrogen). [Selection diagram] None |