| abstract |
PROBLEM TO BE SOLVED: To provide an enzymatic nucleic acid containing a chemically synthesized non-nucleotide. SOLUTION: A nucleic acid comprising at least one non-basic nucleotide, wherein the nucleic acid molecule has an abasic nucleotide incorporated therein by using a compound selected from the group consisting of compounds represented by the following compounds 4 and 5. Provide molecules. Embedded image Wherein DMT is dimethoxytrityl, CEO is cyanoethyl, R is selected from the group consisting of H, OH, protected OH, O-alkyl, alkyl, alkenyl and alkynyl, wherein O-alkyl, alkyl, alkenyl or Alkynyl groups have from 1 to 10 carbon atoms]. [Selection diagram] None |