| abstract |
PROBLEM TO BE SOLVED: To provide a liposome useful for prevention or treatment of a bone disease and a lipid as a raw material thereof. The phospholipid represented by the formula I is modified with a silyl group having at least one hydroxyl group. A liposome containing the phospholipid. (R 1 , R 2 and R 3 are a hydroxyl group which may be protected, and R 4 and R 5 are C7 to C30, a part of which may form an aromatic ring; , X is a spacer, and m and n are 0 or an integer of 1-3.) [Selection diagram] None |