| abstract |
An inhalant containing a neutrophil elastase inhibitor comprising a five-membered heterocyclic compound represented by the formula (I) or a non-toxic salt thereof, particularly an inhalant for respiratory diseases. Embedded image (In the formula, one of X and Y represents -N =, the other represents -NH-, -NR 2- , -O- or -S-, and when X represents -N =, the bond α And the bond β are a double bond and a single bond, respectively, and when Y represents -N =, the bond α and the bond β are a single bond and a double bond, respectively.) [Effect] The inhalant of the present invention inhibits neutrophil elastase because it inhibits neutrophil elastase, especially respiratory diseases such as chronic obstructive pulmonary disease (COPD), acute lung injury, and pulmonary fibrosis. It is useful for treatments such as. [Selection diagram] None |