| abstract |
Kind Code: A1 A cell division visualizing cell capable of visualizing cell division by introducing a fluorescent protein into the cell, a method for producing the cell, a method for visualizing cell division using the cell, a method for evaluating the effect on cell division, and screening. Provide a method. The present invention provides (1) a fusion gene obtained by fusing a gene of a protein constituting a cell structure reflecting the state of cell division with a gene of a fluorescent protein, and (2) A cell division visualized cell is obtained by introducing three or more types of the above-mentioned fusion genes having different types of fluorescent proteins into a host cell, and then (3) expressing the fluorescent protein and cell division of the cell division visualized cell At times, cell division is visualized by detecting the fluorescence derived from the fluorescent protein over time, and the state of cell division is observed. Further, by co-culturing the test substance and the cell division visualizing cell of the present invention, a test substance that affects cell division can be selected. [Selection diagram] Fig. 1 |