| abstract |
[PROBLEMS] To provide a polynucleotide derivative capable of easily and accurately identifying a nucleobase, a nucleoside or nucleotide derivative and a base compound which can be used as an intermediate thereof. A pyrimidine compound represented by the following general formula (1), a nucleoside nucleotide derivative, a polynucleotide derivative, and a polynucleotide derivative containing the same are used. Embedded image (Wherein, R 1 , R 2 , R 3 , and R 4 are the same or different from each other, and represent a hydrogen atom, an amino group, a mono- (lower alkyl) amino group, a di- (lower alkyl) amino group, a hydroxyl group, an alkyl group A lower alkoxy group, a lower alkylthio group, an alkylthio group, an acyloxy group, a halogen atom, a cyano group, a thiol group or a phenyl group which may have a substituent, and R 1 , R 2 , R 3 and R 4 are simultaneously R 1 and R 2 , R 2 and R 3 , and R 3 and R 4 may combine to form a phenyl group.) [Selection] Fig. 2 |