http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004166615-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_274c89a665d51eb0a8888c4d01de6cb0
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
filingDate 2002-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3235a0022f76a33af1f584643e816059
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07b89bd0354c0d6753bb7ab3cc412985
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89c47d4bd81c99d06bb3db88947f0f5d
publicationDate 2004-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2004166615-A
titleOfInvention Single nucleotide polymorphism in schizophrenia-related metabotropic glutamate receptor gene and method for identifying the same
abstract A novel SNP associated with schizophrenia in a schizophrenia-related metabotropic glutamate receptor type 7 gene (GRM7) and a method for identifying the same are provided. A polymorphism analysis between a novel single nucleotide polymorphism (SNP) in a schizophrenia-related metabotropic glutamate receptor type 7 gene (GRM7) and a known SNP (rs1569286) shows that gene SNP in which the base cytosine (C) having the base number 506852 was replaced with the base guanine (G) was significantly associated with schizophrenia. That is, when the allele frequency was compared between the affected group and the healthy group in each SNP, there was a significant association with schizophrenia (p = 0.999). When a haplotype using two SNPs was constructed and linkage disequilibrium analysis was performed, the haplotype was similarly significantly associated with schizophrenia (p = 0.0069). [Selection diagram] None
priorityDate 2002-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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