| abstract |
An object of the present invention is to provide a therapeutic agent for diseases caused by circulatory disorders, which comprises an indenone derivative or a pharmacologically acceptable salt thereof as an active ingredient. The formula (I) Embedded image In the formula, R 1 and R 2 are the same or different and represent hydrogen, hydroxy, or the like; R 3 represents cyano, carboxy or lower alkoxycarbonyl; R 4 is formyl, carboxy, formula (a) wherein X represents CH or N, R 9 represents hydrogen, R 10 and R 11 represent hydrogen, or R 10 and R 11 together Wherein R 12 and R 13 are the same or different and represent hydrogen or lower alkyl, W 1 and W 2 are the same or different, and CR 14 (where R 14 is hydrogen Or a group represented by lower alkyl) or N)]. And a pharmacologically acceptable salt thereof as an active ingredient. [Selection diagram] None |