http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004131462-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ef01e33058cf740cf2197991be97af1 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-60 |
| filingDate | 2003-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7238a2834c2e716929c05e908dd82500 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6993a4e9a4243c9d93624123e86fe549 |
| publicationDate | 2004-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2004131462-A |
| titleOfInvention | Optically active azole derivative and method for producing the same |
| abstract | An optically active 2-phenyl-2,3-dihydroxypropylazole derivative, which is a useful compound in the field of medicine and agrochemicals, and which is particularly important in the production process of an optically active azole antifungal agent, The present invention provides a low-cost and stable production method and a novel intermediate in a short process. An optically active α-hydroxycarboxylic acid derivative represented by the general formula (1) is reacted with an azole acetic acid derivative (2) to produce a novel optically active azole alkyl ketone derivative (3). I do. Furthermore, a novel optically active azole methyl alcohol derivative (5) is produced by a highly diastereoselective alkylation reaction using a combination of a protecting group and an organometallic reagent (4). Further, by selectively deprotecting, an optically active 2-phenyl-2,3-dihydroxypropylazole derivative (6) is produced. [Selection diagram] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018124172-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10919829-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2018124172-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7111625-B2 |
| priorityDate | 2002-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 169.