| abstract |
A novel compound that binds to FKBP12 is provided. SOLUTION: The following formula: [Wherein, R 1 represents a C 1-8 alkylsulfonyl group, a C 1-8 alkyloxazaryl group or a compound of the formula: Wherein R 3 is a C 3-8 cycloalkyl group, R 4 is a hydrogen atom, or R 3 and R 4 together with an adjacent carbon atom form one of the C 1-3 alkyl groups. a group forming a substituted C 3-8 cycloalkyl group or a C 3-8 cycloalkyl group to four, R 5 is a group represented by a hydrogen atom or a hydroxyl group.), R 2 Is a phenyl group or a pyridyl group, and n is 1 or 2. Or a pharmaceutically acceptable salt thereof. [Selection diagram] None |