| abstract |
A method of rationally designing a granulocyte colony stimulating factor (G-CSF) analog and related compositions and a G-CSF analog obtained thereby. The present invention provides granulocyte colony stimulating factor (G-CSF) analogs, compositions comprising the analogs, and related compositions. Also provided are nucleic acids or related nucleic acids encoding the analogs, related host cells and vectors. In another aspect, there is provided a computer program and apparatus for representing the three-dimensional structure of G-CSF and its analogs. [Selection diagram] None |