abstract |
[Problem] To provide a novel protein having activity such as K + ion permeation, a DNA encoding the protein, a method for screening a compound that promotes or inhibits the activity of the protein, a compound obtained by the screening method, and the like. Kind Code: A1 A protein having the same or substantially the same amino acid sequence as the amino acid sequence represented by a specific sequence includes, for example, digestive diseases, immune diseases associated with thymic abnormalities, pancreatic diseases, diabetes, genital diseases, central diseases, etc. Compounds that are useful as diagnostic markers for nervous system diseases, cardiovascular diseases, muscular diseases, cancers and the like, and that promote or inhibit the activity of the protein obtained by a screening method using the protein include, for example, the prevention of the above-mentioned diseases. -It can be used as a therapeutic agent. [Selection diagram] None |