| abstract |
PROBLEM TO BE SOLVED: To provide texaphyrin for radiosensitization and to enhance radiation damage by this texaphyrin and to overcome many of the disadvantages of prior art radiosensitizers. The use of texaphyrin in the preparation of a pharmaceutical composition for use as a radiosensitizer, wherein texaphyrin is an aromatic pentadentate macrocycle, "expanded porphyrin," Due to the lipophilicity of texaphyrin, it shows greater biolocalization in neoplastic tissues and atheromas, in relation to non-neoplastic tissues and non-atheroma plaques, which are benign or malignant tumors Get, use. [Selection diagram] None |