abstract |
The present invention provides a novel transcription factor, its DNA and use. The protein of the present invention is a diagnostic marker for a nervous system disease and has a cholinergic neuronal differentiation inhibitory action. Compounds or salts thereof that regulate (preferably inhibit) the activity of the protein of the present invention or the expression of the protein gene of the present invention, the antisense polynucleotide of the present invention, the antibodies of the present invention, etc. are excellent in promoting cholinergic neuronal differentiation. It can be used as a prophylactic / therapeutic agent for nervous system diseases as an agent. [Selection diagram] None |