abstract |
An object of the present invention is to provide a compound that can be used for treating various diseases in which CCR3 is involved. For example, at least three of 2- (1-benzoylpiperidin-4-ylidene) -N- {1-[(6-fluoronaphthalen-2-yl) methyl] pyrrolidin-3-yl} acetamide are provided. The present inventors have found that an acrylamide derivative having a cyclic group having a good CCR3 antagonistic activity and is effective in treating CCR3-related diseases such as asthma, and thus completed the present invention. [Selection diagram] None |