| abstract |
【Task】 To provide an agent for inhibiting abnormal postnatal axial growth of the eye of a mature animal during the postnatal maturation period of the animal. [Solution] An agent for inhibiting abnormal postnatal axial growth of the eye of a mature animal during the postnatal maturation period, comprising a therapeutically effective amount of relatively brain, neural tissue and / or ganglion cells M 1 is cholinergic receptors in that block is selective, in that block M 3 cholinergic receptors in cells of the smooth muscle in the front of the eye has a weaker selectivity in, M 3 smooth having an affinity for at least 5 times greater M 1 receptor than for muscle receptor, and comprises an effective muscarinic pharmacological antagonist in inhibiting abnormal postnatal axial growth of the eye (but pirenzepine, telenzepine and (Excluding muscarinic pharmacological antagonists, which are tricyclic compounds). |