| abstract |
An alkyl-8-nitroxanthine derivative represented by the following general formula (1): (Wherein, R 1 and R 2 each independently represent a methyl group or an alkyl group having 2 to 5 carbon atoms, and at least one of R 1 and R 2 is an alkyl group having 2 to 5 carbon atoms), and A medicine containing this as an active ingredient. [Effect] The compound (1) of the present invention has an excellent hypoxic live cell radiosensitizing effect and is highly safe, and is useful as a medicament such as a hypoxic cellular radiosensitizer. [Selection diagram] None |