abstract |
The present invention relates to a selectin variant having an amino acid change at a site in the selectin lectin domain amino acid sequence within a region defined by a binding site recognized by a blocking monoclonal antibody against a corresponding selectin in which the lectin domain is not changed. Things. A nucleotide sequence encoding such a variant, an expression vector comprising such a nucleotide sequence, and a host cell transformed with such an expression vector are also within the scope of the present invention. [Selection diagram] None |