| abstract |
The present invention provides a novel phosphonic acid diester derivative as an active pharmaceutical ingredient. SOLUTION: The general formula: [In the formula, two Rs each represent a lower alkyl group. -A- represents -Ph-CH 2 - represents a group or a single bond. When B is -A- is a single bond, 8H-indeno indicates [1,2-d] thiazol-2-yl group, -A- is -Ph-CH 2 - when group, the following group (1) - (3) Embedded image (R 1 , X 1 , Y 1 , -Z 1 -in group (1), -X 2 -Y 2 -Z 2- in group (2) and -X 3 in group (3) in each group —Y 3 —Z 3 — is as described in the text). A phosphonic acid diester derivative represented by the formula: [Selection diagram] None |