abstract |
An immunoassay for an antibody against hepatitis C virus in a sample solution and a method for early recognition of HCV seroconversion are provided. A sequence region from the NS3 region of hepatitis C virus, comprising at least one cysteine residue and wherein the cysteine residue is covalently modified or substituted with another amino acid. The sample solution is incubated with at least one polypeptide and binding of the antibody to the polypeptide is detected in a reduced state. [Selection diagram] None |