| abstract |
PROBLEM TO BE SOLVED: To provide a derivative or analog of baccatin III or 10-desacetyl baccatin III having a C9 substituent other than keto. SOLUTION: Taxol, a taxol analog, baccatin III or 10-desacetyl baccatin III is subjected to a method wherein the C9 keto substituent is selectively reduced to the corresponding hydroxyl group. [Selection diagram] None |