| abstract |
(57) [Summary]n Disclosed are macromolecular drug conjugates containing a drug such as human growth hormone and a polymer having a plurality of acid moieties such as carboxyl or phosphonic acid moieties, and compositions containing the same. A composition containing the macromolecular drug conjugate, especially a microemulsion, is administered to an individual suffering from a disease or condition, which releases the drug in vivo to treat the disease or condition. And reduce, eliminate or ameliorate the complications associated with the disease. |