abstract |
(57) The present invention relates to an active ingredient represented by the formula (I): Wherein R is an -alk-S-alk-Ar group, a phenyl group, or a phenyl group substituted with alkoxy or halogen, 4,5-dihydro-1,3-thiazol-2-ylamine derivative or The present invention relates to a pharmaceutical composition containing the pharmaceutically acceptable salt thereof, a novel derivative of the formula (I) and a method for producing them. This compound is useful for the prevention and treatment of diseases involving abnormal production of nitric oxide (NO) due to induction of inducible NO synthase. |