| abstract |
(57) [Summary]nA method for producing a biodegradable polymer micelle composition using liquid polyethylene glycol as a phase separation medium, the phase separation comprising an effective amount of a hydrophobic drug, an amphiphilic block copolymer, and liquid poly (ethylene glycol). Mixing a medium, stirring and heating to obtain a solution; cooling and stirring the solution until a polymer micelle is formed by phase separation; diluting the polymer micelle solution with distilled water and then adding Dialysis with an amount of water to remove liquid polyethylene glycol; and freeze-drying the dialysis aqueous solution to obtain a powdery polymer micelle composition. |