http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003530073-A
Outgoing Links
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|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-544 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5254 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5256 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18522 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate | 2000-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2003-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2003530073-A |
| titleOfInvention | Production of an attenuated human-bovine chimeric respiratory syncytial virus vaccine |
| abstract | Summary Chimeric human-bovine respiratory syncytial virus (RSV) is infectious, attenuated in humans and other mammals, and is useful in vaccine formulations to elicit an anti-RSV immune response. is there. Further provided is a combination or integration of a partially or completely human or bovine RSV "background" genome or antigenome with one or more heterologous genes or one or more genomic segments of different RSV strains. Isolated polynucleotide molecules and vectors that have incorporated the encompassing chimeric RSV genome or antigenome. The chimeric human-bovine RSV of the present invention comprises a partial or complete "background" RSV genome or antigenome derived or mimicked from a human or bovine RSV strain or subgroup virus, different RSV strains or subgroups. Included are those that form a human-bovine chimeric RSV genome or antigenome in combination with one or more heterologous genes or one or more genomic segments of the virus. In a preferred embodiment of the invention, the chimeric virus incorporates a partial or complete bovine RSV background genome or antigenome in combination with one or more heterologous genes or genomic segments from one or more human RSV. Genes of interest include any of the NS1, NS2, N, P, M, SH, M2 (ORF1), M2 (ORF2), L, F or G genes or any genomic segment containing a protein thereof. Included. Various additional mutations and nucleotide modifications are encompassed by the human-bovine chimeric RSV of the present invention to achieve the desired phenotypic and structural effects. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2007060725-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014236748-A |
| priorityDate | 1999-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 609.