| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-645 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-645 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 |
| filingDate |
2001-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2003-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2003529585-A |
| titleOfInvention |
Chemokine receptor antagonist |
| abstract |
(57) [Summary]nA novel tetramic acid-type compound isolated from the CCR5 active complex, produced under controlled conditions by fermentation of a biologically pure culture of the microorganism Chaetomium globosum Kunze SCH 1705, ATCC 74489. Disclosed are pharmaceutical compositions, as well as the use of CCR5 antagonist compounds and compositions for treating HIV-1 infection in humans. The present invention also provides for the administration of a therapeutically effective amount of HAART together with a therapeutically effective amount of a compound of Formula I, II or III sufficient to reduce HIV-1 RNA. A method of treating a patient having |
| priorityDate |
2000-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |