| abstract |
(57) The compounds of the present invention are useful in inhibiting thrombin and related thrombotic occlusions and are selected from group (I) or a pharmaceutically acceptable salt thereof, wherein T is group (II) is selected from and (III); D, E, F, G, H, I and J is N or CY 1 independently, but such variables D, E represents an N, F, G, The number of H, I and J is zero, one or two; K, L, M and Q are independently NH or CY 1 Y 2 , provided that such variables D, E, F, K, L, M and Q are 0, 1 or 2; Y 1 and Y 2 are independently selected from the group consisting of hydrogen, C 1-4 alkyl, halogen, amino or hydroxyl; A is (IV), (V), (V) or (VII). ]. Embedded image |