abstract |
(57) [Summary]nSOLUTION: A dosage form for at least one solid reagent for use in customary organic and inorganic synthesis, parallel synthesis, and split and mix synthesis in combinatorial chemistry, is dissolved in a solvent insoluble for the intended synthesis. Provided as a compressed tablet containing a predetermined substantially the same amount of at least one reagent embedded in a polymer matrix comprising beads of the polymer. The polymer beads forming the matrix and the reagents in the dosage form can be easily removed by filtration to separate it from the resulting soluble product. In one method of preparing a dosage form, beads of one or more polymers are mixed with reagents and compressed into tablets after pre-treatment with an aprotic organic solvent. |