abstract |
(57) [Summary] Formula (I) Wherein Ar 1 , R a , R 4 , R 5 , X and Y are as defined herein, which are useful as inhibitors of certain protein tyrosine kinases. And thus treating diseases associated with such kinases, such as diseases resulting from inappropriate cell proliferation, including autoimmune diseases, chronic inflammatory diseases, allergic diseases, transplant rejections and cancer. It is informative. Also disclosed are methods of preparing these compounds, novel intermediates useful in these methods, and compositions comprising compounds of formula (I). |