| abstract |
SUMMARY A polysaccharide-coated carrier having at least two continuous layers of a polysaccharide coating is disclosed. The first polysaccharide layer is naturally associated with the second polysaccharide layer and optionally the carrier. Each successive polysaccharide layer spontaneously associates with the immediately preceding layer. Spontaneous binding occurs due to the presence of functional groups having opposite charges in each polysaccharide layer or by a natural reaction between the functional groups in each layer. The carrier is a surface such as a tube, microtiter plate, beads, particles, etc., which is suitable for use in a diagnostic or therapeutic method. |