| abstract |
(57) [Summary]nCompositions for stabilizing polynucleic acids and increasing the ability of polynucleic acids to cross cell membranes and function inside cells. In one aspect, the invention provides a polynucleotide conjugate of the polynucleotide with certain polyether block copolymers. The polynucleotide conjugate can further include a polycationic polymer, and a suitable targeting molecule and surfactant. The invention also provides a polynucleotide complex of the polynucleotide with a block copolymer comprising a polyether block and a polycation block. |