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filingDate 2001-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2003-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2003525903-A
titleOfInvention New uses of cholinesterase inhibitors
abstract (57) [Summary]nThe present invention relates to dementia due to vascular disease; dementia associated with Parkinson's disease; dementia associated with Lewy bodies; AIDS dementia; mild cognitive impairment; age-related memory impairment; epilepsy, brain tumor, brain injury, multiple sclerosis, down syndrome, Cognitive impairment and / or dementia associated with neurological and / or mental states, including Rett syndrome, progressive supranuclear palsy, frontal lobe syndrome, and schizophrenia and related psychiatric disorders; traumatic brain injury, sequelae of coronary artery bypass graft surgery, Novel methods for treating and preventing cognitive impairment due to ectotherapy and chemotherapy by administering a therapeutically effective amount of at least one cholinesterase inhibitor compound described herein. The present invention also provides a method for administering delirium, Tourette's syndrome, myasthenia gravis, attention deficit hyperactivity disorder, autism, by administering at least one therapeutically effective amount of a cholinesterase inhibitor compound described herein. Novel methods for treating and preventing dyslexia, mania, depression, depression, and myopathy associated with diabetes are also described. The present invention also provides for treating and preventing sleep apnea, delaying the onset of Alzheimer's disease, enhancing cognitive function, and administering a therapeutically effective amount of at least one cholinesterase inhibitor compound described herein. Novel methods for alleviating tobacco withdrawal syndrome as well as treating dysfunction of Huntington's disease are also described. A preferred cholinesterase inhibitor for use in the methods of the present invention is donepezil hydrochloride or AriceptĀ®.
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