http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003523955-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343 |
| filingDate | 2001-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2003-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2003523955-A |
| titleOfInvention | Method for producing citalopram |
| abstract | (57) The Abstract: The present invention is represented by formula (I) compounds, formula (II) {wherein, X is a suitable leaving group, R represents -CH 2 -O-Pg, -CH 2 -NPg 1 Pg 2, -CH 2 -NMePg 1, -CO-N (CH 3) 2, -CH (OR 1) (OR 2), - C (OR 4) (OR 5) (OR 6), - COOR 3 , —CH 2 —CO—NH 2 , —CH ＝ CHR 7 or —CO—NHR 8 , wherein Pg is a protecting group for an alcohol group, and Pg 1 and Pg 2 are protecting groups for an amino group. And R 1 and R 2 are independently selected from an alkyl group, an alkenyl group, an alkynyl group and an optionally alkyl-substituted aryl residue or an aralkyl group, or R 1 and R 2 together represent 2 to 4 R 3 , R 4 , R 5 , R 6 and R 7 are each independently It is selected from an alkyl group, an alkenyl group, an alkynyl group and an optionally alkyl-substituted aryl residue or an aralkyl group, and R 8 is hydrogen or methyl. To give a compound of the formula (III) (wherein R has the meaning given above), then convert the group R to a dimethylaminomethyl group and then citalopram base or The present invention relates to a method for producing citalopram, comprising isolating a pharmaceutically acceptable salt thereof. Embedded image |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010527345-A |
| priorityDate | 2000-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 100.