| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0073 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522 |
| filingDate |
2001-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2003-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2003523393-A |
| titleOfInvention |
Metalloproteinase inhibitors for the treatment of respiratory diseases |
| abstract |
(57) [Summary]nUse of a compound for the manufacture of a medicament for treating a respiratory disease associated with tissue destruction, which compound exhibits an inhibitory activity of inhibiting MMP1 or MMP2 or MMP8 or MMP9 by 50% or more at a concentration of 100 μM or less in an enzyme assay. And down-regulate MMP1 or MMP2 or MMP8 or MMP9 in COPD lung tissue at 100 μM to less than 50% of the untreated concentration. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008201790-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016130258-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007528409-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011140511-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4737648-B2 |
| priorityDate |
2000-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |