| abstract |
(57) Abstract The present invention relates to a novel derivative of andrographolide, its stereoisomer, its polymorph, its pharmaceutically acceptable salt, and its pharmaceutically acceptable solvate. The novel derivatives of andrographolide have the general formula (I). The andrographolide derivative represented by the general formula (I) as defined above of the present invention is an antiviral for the treatment of cancer, HSV, HIV, psoriasis, restenosis, atherosclerosis, and other cardiovascular diseases. Useful as drugs, antimalarials, antibacterials, hepatoprotectives, immunomodulators, and in the treatment of metabolic disorders. Embedded image |