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filingDate 2001-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2003-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2003521532-A
titleOfInvention Method for selectively crystallizing sodium 3-pyridyl-1-hydroxyethylidene-1,1-bisphosphonate as 2.5 hydrate or monohydrate
abstract (57) [Summary]nThe present invention relates to sodium 3-pyridyl-1-hydroxyethylidene-1.1-bisphosphonate 2.5 hydrate and monohydrate, and 2.5 hydration by controlling the nucleation temperature and crystallization rate. A method of preparing a product or monohydrate and a pharmaceutical composition containing one or both forms of the hydrate are disclosed.
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