| abstract |
(57) [Summary]nThe present invention relates to novel imidazolidinone derivatives, their synthesis and their use as αv integrin receptor antagonists. In particular, the compounds of the invention are antagonists of the integrin receptors αVβ3 and / or αVβ5, inhibiting bone resorption, treating and preventing osteoporosis, and vascular restenosis, diabetic retinopathy, macular degeneration, angiogenesis, Useful for inhibiting atherosclerosis, inflammation, inflammatory arthritis, viral diseases, cancer and metastatic tumor growth. |