| abstract |
(57) Abstract The present invention provides a bioerodible construct for controlled release of a bioactive substance. In a preferred form, the construct can be used adjacent to a biological surface. The construct is based on a blend of two or more poly (ester-amide) polymers (PEA). Such polymers can be prepared by polymerizing diol (D), dicarboxylic acid (C) and α-amino acid (A) in the form of (DACA) n via ester and amide bonds. (DACA) Examples of n- polymers are shown in Formula II below. Suitable amino acids include natural or synthetic α-amino acids, preferably neutral amino acids. |