abstract |
(57) The present invention relates to a compound of the formula (I) wherein W is C, CH or N, and the dotted line emerging from W indicates a bond when W is C; When W is N or CH, it indicates no bond; R 1 and R 2 are independently selected from hydrogen and halogen, provided that at least one of R 1 and R 2 is a halogen atom X is CH 2 , O, S, CO, CS, SO, or SO 2 ; Q is a group of formula (II), wherein X is a group wherein Q is an N atom A substituted 4-phenyl-l-piperazinyl derivative having the formula (I) when attached via a bond, but neither O nor S), and any of its enantiomers and acid addition salts thereof. These compounds have a high affinity for D 4 receptors. Embedded image |