| abstract |
(57) Abstract: 5-HT reuptake and de - providing dopamine D 2 receptor antagonism inhibits a useful psychosis and depression agent to a compound. SOLUTION: A compound of the formula (I), wherein Ar is selected from (a) and (b), Z is (II) or (III), Y is oxygen or sulfur, R 1 and R 4 is independently selected from hydrogen and lower alkyl; R 5 is selected from hydrogen, halogen, lower alkoxy and cyano; R 6 and R 7 are independently selected from hydrogen, halogen and lower alkoxy. , M is an integer of 2-6, n is zero, or an integer of 1 or 2, and the dotted line is any double bond. Ar-Y- (CH 2) m -Z (I) ## STR1 ## |