abstract |
(57) Abstract: A series of adenosine-5'-uronamide derivatives having an N 6 -arylurea, alkarylurea, heteroarylurea, arylcarbonyl, alkarylcarbonyl or heteroarylcarbonyl group, wherein adenosine A 1 , or affinity for a 3 receptors, and, in some instances, have been disclosed what has selectivity. These compounds, in pharmaceutical compositions for the treatment of disorders caused by A 1 or A 3 receptor overactivity, or clinical applications for detecting the relative binding of another compound to the A 1 or A 3 receptors Can be used. |