| abstract |
(57) Abstract Multifunctional polyionic copolymers are synthesized or / and applied to a substrate surface for analytical and sensing purposes. These coatings are particularly useful for suppressing non-specific interactions, adsorption or binding. The groups can be attached, integrated or adsorbed to a multifunctional polymer capable of recognizing, interacting and specifically binding the target analyte molecule. These materials can also be used to modulate biological interactions on a substrate surface for use as a selective implant surface, which resist cell attachment and, if necessary, specific types Can promote cell attachment or induce specific cell behavior. Multifunctional polymer coatings are typically brushes based on polycationic or polyanionic scaffolds with side chains that control interaction with the environment or that reduce cell adhesion, as well as analyte-specific side chains. Including copolymers. |