http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003515586-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-34 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14 |
filingDate | 2000-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2003-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2003515586-A |
titleOfInvention | Acryloyl peptide derivatives, their preparation, and their use as antitumor agents |
abstract | (57) Abstract: An acryloyl peptide derivative of the formula (I) wherein n is 3 or 4, m is 0, 1 or 2, X and Y are the same or different and are independent for each heterocycle. Wherein R 1 and R 2 are the same or different and are selected from hydrogen, halogen, or C 1 -C 4 alkyl; R 3 is hydrogen or halogen; and B is a group of formula (1), ( Selected from the group consisting of 2), (3), (4), (5), (6), and (7), wherein R 4 , R 5 , R 7 and R 8 are each independently hydrogen or C 1 CC 4 alkyl, and R 6 is hydrogen, hydroxy, or C 1 -C 4 alkyl, provided that X and Y are not both N atoms for the same heterocycle and all X and Y Is a CH group and m is 0, R At least one of R 4 , R 5 , or R 6 is other than hydrogen, and when at least one of X and Y is other than CH, at least one of R 4 and R 5 is other than hydrogen Or a pharmaceutically acceptable salt thereof is useful as an antitumor agent. Embedded image |
priorityDate | 1999-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 177.