| abstract |
(57) [Summary]nPatients susceptible or afflicted with pathological conditions and diseases such as central nervous system disorders include those in need of such aryl olefin azacyclic compounds, including pyridyl olefin cycloalkylamines and pyridyl acetylene cycloalkylamines. And by administering an arylacetylene azacyclic compound. Typical compounds are (S)-(E) -3- (3-pyrrolidin-2-yl-prop-1-enyl) pyridine, (S)-(E) -3- (2-pyrrolidin-2- Ylvinyl) pyridine, 3- (2-pyrrolidin-2-ylethenyl) pyridine, 3- (3-pyrrolidin-2-ylprop-1-enyl) pyridine, 3- (2- (2-azetidinyl) ethenyl) pyridine, 3- (3- (2-azetidinyl) prop-1-enyl) pyridine, 2- (2- (3-pyridyl) ethenyl) -1-azabicyclo [3.3.0] octane, 2- (3- (3-pyridyl) ) Prop-2-enyl) -1-azabicyclo [3.3.0] octane, 3- (2- (3-pyridyl) ethenyl) -2-azabicyclo [2.2.1] heptane, 3- (3- (3-pyridyl) prop-2-any ) -2-Azabicyclo [2.2.1] heptane, 2- (2- (3-pyridyl) ethenyl) -7-azabicyclo [2.2.1] heptane, 2- (3- (3-pyridyl) prop -2-enyl) -7-azabicyclo [2.2.1] heptane, 2- (2- (3-pyridyl) ethenyl) quinuclidine, and 2- (3- (3-pyridyl) prop-2-enyl) Contains quinuclidine. |